Two Novel ATP2C1 Mutations in Portuguese Patients with Hailey-Hailey Disease
Hailey-Hailey disease (HHD) is a rare autosomal dominant acantholytic dermatosis.It is characterized by a recurrent eruption of vesicles, erosions, and scaly erythematous plaques involving canadian white blenheim apricot intertriginous areas and first occurring after puberty, mostly in the third or fourth decade.In 2000, mutations in the ATP2C1 gen